smith nephew plc

Below is a listing of stocks making meaningful moves in pre-open trading Wednesday: HIGHER: ADA-ES, Inc.

(NASDAQ: ADES) 16% HIGHER; Settlement Agreement with Norit America Cell Therapeutics, Inc. (NASDAQ: CTIC) 14% HIGHER; Russell rebalance Zipcar, Inc.

(NYSE: ZIP) 10% HIGHER; deal with Ford Vera Bradley, Inc. (NASDAQ: VRA) 8% HIGHER; Q2 results Joy Global, Inc.

(NASDAQ: JOYG) 4% HIGHER; post Q3 results, lifts outlook Sina Corp. (NASDAQ: SINA) 4% HIGHER; takeover rumor JOS A Bank Clothiers, Inc.

(NASDAQ: JOSB) 3% HIGHER; tops Q2 views PVH Corp.

NUCRYST Pharmaceuticals Corp. (NASDAQ: NCST) 69% HIGHER; announced today the execution of a definitive agreement with subsidiaries of Smith & Nephew plc.

(NYSE: SNN) for the sale to Smith & Nephew of substantially all of Nucryst's operations and assets including all rights to its proprietary nanocrystalline silver technology for cash consideration of $21 million plus the value of working capital and subject to certain adjustments.